Question

Which chromosomes carry the mutant genes causing thalassaemia in humans ? What are the problems caused by these mutant genes ?

Answer 1

Answer:

Beta thalassemias are due to mutations in the HBB gene on chromosome 11, also inherited in an autosomal, recessive fashion.

Answer 2

Chromosomes carry the mutant genes causing thalassaemia in humans and the problems caused by these mutant genes:

• Thalassemia is inherited by blood tissue disorder which is characterized by abnormal hemoglobin production.
• Beta thalassemia is caused due to mutation in the genes on chromosome-11.
• There may be bone problems, an enlarged spleens, yellowish skin and dark urine etc..,
• Alpha thalassemia have no symptoms and no treatment and occurs when body producing alpha globin.