Biology, asked by ananshu966, 8 months ago

which enzyme does remove supercoils from replicating DNA

Answers

Answered by nikita6075
5

Answer:

topoisomerase......

Answered by ashok22122002
7

Explanation:

The first type II topoisomerase (Topo II) to be described was isolated from E. coli. and named DNA gyrase. Topo II enzymes have the ability to cut both strands of a double-stranded DNA molecule, pass another portion of the duplex through the cut, and reseal the cut in a process that utilizes ATP . Depending on the DNA substrate, these maneuvers will have the effect of changing a positive supercoil into a negative supercoil or of increasing the number of negative supercoils by 2. The Topo II enzymes from mammalian cells cannot, like E. coli DNA gyrase, increase the superhelical density at the expense of ATP; presumably no such activity is required in eukaryotes, since binding of histones increases the potential superhelicity. All type II topoisomerases catalyze catenation and decatenation, that is, the linking and unlinking, of two different DNA duplexes . Action of E. coli DNA gyrase, a type II topoisomerase.

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