Question

Which enzyme removes the rna primer and fills in deoxyribonucleotides in prokaryotic replicase?

Answer 1

 RNase H removes the RNA primer (created by primase) from the lagging strand and then polymerase I fills in the necessary nucleotides between the Okazaki fragments (see DNA replication) in a 5'→3' direction, proofreading for mistakes as it goes.