Which factor is responsible for inhibition of enzymatic process during feed back :
Answers
Feedback inhibition is the phenomenon where the output of a process is used as an input to control the behavior of the process itself, oftentimes limiting the production of more product. Although negative feedback is used in the context of inhibition, negative feedback may also be used for promoting a certain process. An everyday example of negative feedback is the cruise control in automobiles. The faster a car goes above the cruise control speed, the stronger the brakes are applied to slow the car down. If the car is going too slowly, more gas is fed to the engine to speed the car up. In a biological context, the more product produced by the enzyme, the more inhibited the enzyme is towards creating additional productMany enzyme catalyzed reactions are carried out through a biochemical pathway. In these pathways, the product of one reaction becomes the substrate for the next reaction. At the end of the pathway, a desired product is synthesized. In order to tightly regulate the concentration of that product, the biochemical pathway needs to be shut down. This is done through feedback inhibition. The product of the final reaction in that pathway reacts with an enzyme somewhere along the pathway at the enzyme's allosteric site, changing the conformation of the enzyme. That enzyme can no longer bind to its substrate as effectively due to the conformational change, closing down that pathway and stopping the final product from synthesizing. The higher the concentration of the final product, the more likely that product will bind to the allosteric site of the enzyme, shutting down that pathway.
Options are not provided in the question. The complete question is as follwoing:
Which factor is responsible for inhibition of enzymatic process during feed back :-
(1) Substrate (2) Enzymes (3) End product (4) Temperature
Answer:
The concept is based on feedback inhibition.
Explanation:
Feedback inhibition is a cellular control mechanism in which the end product of an enzyme inhibits the action of an enzyme. This mechanism enables the cells to control how much of the end product of an enzyme is generated.
Allosteric sites present in an enzymes help to proceed feedback inhibition. An end product binds to allosteric site in an enzymes and changes the shape and behaviour of active site in the enzyme. It slows the down the enzyme activity and no new product is form.
Hence, the correct otpion is (3) End product.
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