Question

Which is an example Which is an example of a deletion mutation that results in a new protein of a deletion mutation that results in a new protein

Answer 1

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In genetics, a deletion (also called gene deletion, deficiency, or deletion mutation) (sign: Δ) is a mutation (a genetic aberration) in which a part of a chromosome or a sequence of DNA is lost during DNA replication.

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Answer 2

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The following is an example of a single nucleotide deletion mutation. The short sequences of DNA are not representative of actual DNA, which contains many hundreds or thousands of base pairs. The top string represents the original strand of DNA, while the bottom strand lacks the nucleotide pair removed by the deletion mutation. The triplet codons are separated, to see the effects of the deletion mutation.

5’ TAC CCA GGG 3’

3’ ATG GGT CCC 5’

5’ TAC CCA GG 3’

3’ ATG GGT CC 5’

As you can see, if this were the end of the DNA molecule, the last amino acid would not be produced. Instead, a deletion mutation will usually occur in the middle of a chromosome or gene. This will cause the deleted nucleotide to be filled by shifting the DNA and causing a frameshift mutation, or inserting a new nucleotide in a mutation known as an insertion. This mutation can only be passed on if the organism’s mechanisms for repairing DNA do not catch the mistake, and the DNA exists in a cell that will produce offspring. In asexual organisms, this is every cell and mutations are more likely to persist. In sexually reproducing organisms, mutations can only be passed on if they arise in the gamete producing tissues of the sex organs.