Which is the most efficient way to avoid DNA mutations from UV radiation?
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Sunscreen is the best and most efficient way to avoid DNA mutations. UV radiation causes thymine dimers in the DNA complex, so limiting UV radiation is key to avoid DNA mutations
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UV light causes specific changes in the cellular and epidermal genome, such as UV-signature and triplet mutations, which are hypothesised to be caused by translesion DNA synthesis (TLS) over UV-induced DNA base damage. The UV light from the sun causes a UV-specific mutation. Avoiding UV radiation by applying sunscreen is the most effective approach to avoid DNA changes caused by UV radiation.
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