which is the site of biosynthetic and catabolic activity
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The mammalian liver can both break down glucose for energy and synthesize glucose from food (amino acids, for example). Different reactions and enzymes participate in the catabolic (breakdown) and anabolic (synthetic) directions. The anabolic direction involves the input of energy in the form of ATP hydrolysis.
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More generally, this synthesis occurs in three stages, with the first stage taking place in the cytoplasm and the second and third stages occurring in the endoplasmic reticulum.
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