which lymphocyte form cell mediated immune system ??
Answers
Answer:
Cell mediated immunity (CMI) is that arm of the immune response that does not involve antibodies but rather incorporates the activation of macrophages and NK cells enabling them to destroy intracellular pathogens, the production of antigen-specific CD8 cytotoxic T-lymphocytes (CTLs), and the release of various ..
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Explanation:
Cell-mediated immunity is mediated by T lymphocytes; humoral immunity, by antibodies. These distinctions are based on observations that delayed-type hypersensitivity (DTH) and other manifestations of cell-mediated immunity can be adoptively transferred by lymphoid cells but not by serum from sensitized animals, while other manifestations of immunity can be passively transferred by serum from immune animals. Cell-mediated and humoral immunity can exist in isolation: some chemicals induce contact sensitivity, a manifestation of cell-mediated immunity, but do not induce production of antibodies, and some antigens can stimulate antibody production in the apparent absence of T lymphocytes. However, cell-mediated and humoral immunity usually develop concurrently in vivo, and the two responses often act synergistically. For example, although DTH can be adoptively transferred with T lymphocytes, the intensity of the reaction is usually greater if antibody is also passively administered. There also are conceptual difficulties inherent in these definitions: antibodies are produced by cells, and cells participate in many of the protective reactions mediated by antibodies. Also, T lymphocytes carry out many of their functions through soluble products which they secrete following stimulation with antigen.