Question

which of the following compound is most reactive in nucleophilic substitution reaction​

Answer 1

Answer:

2

is the more reactive nucleophile

Answer 2

Answer:

Therefore from the above explanation we can say that ethanol will be most reactive towards nucleophilic addition reaction.

Note:

There are two important factors that help in comparing the reactivity of aldehydes and ketones in nucleophilic addition reaction and these are steric factor and the electronic factor. More the number of alkyl groups attached to carbonyl carbon more will be the steric hindrance hence less will be the tendency to attack the nucleophile. And if these alkyl groups show positive inductive effect the tendency to attack will be decreased as the electron density increases on carbonyl carbon, thus more the positive inductive effect lesser will be the carbonyl carbon reactivity.

Explanation:

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