Question

Which of the following does not hold true for co-factors? a) Metal ions form co-ordination bonds with both substrate and active site of enzyme b) A co-enzyme can act as co-factors for many different enzymes c) Prosthetic group binds tightly with apo-enzyme d) Co-factors are required for the catalytic activity of all enzymes​

Answer 1

I didn't know about it thank you

Answer 2

correct option is b)

Explanation:

• Co- factor are inorganic metal ions that is required for catalytic activity of enzyme.
• co enzyme are complex organic molecules that is required for catalytic activity of enzyme.
• Both co-enzyme and co-factor binds with apoenzyme loosely or transiently and form holo-enzyme.
• The co-enzymes that bind tightly and permanently to apoenzymes are called prosthetic groups.
• co factors or metal ions contribute to their catalytic process as they can attract and donate the electrons and thus form co-ordination bond with both substrate and active site of enzyme.
• So option b) will not be true for co factors as co-enzyme cannot act as co factor.