Question

Which of the following factors are responsible for the stability of thermophiles at high temperatures?

a. Increased leakage of cell components
b. Presence of large no. of polar amino acids and alpha-helix protein
c. Thermal stability of ribosomes
d. Presence of Inositol diphosphate and thermal stability of ribosomes​

Answer 1

The factor responsible for the stability of thermophiles at high temperatures is the presence of inositol diphosphate and the thermal stability of ribosomes.

So, the correct option is d.

1. Packing, oligomerization, insertions and deletions, proline substitutions, helical content, helical propensities, polar surface area, hydrogen bonds, and salt bridges have all been suggested as variables that contribute to thermophilic protein stability.

2. Increased thermal stability of ribosomes has been implicated in the ability to proliferate at high temperatures.

3. The cytoplasmic membrane of thermophiles also contains inositol diphosphate or triphosphate, which can withstand high temperatures and keep the membrane fluid.