Question

Which of the following groups is least susceptible to cytochrome P450enzyme

Answer 1

Answer:

Exposed groups such as terminal methyl groups are susceptible to oxidation by cytochrome P450 enzymes, as are activated carbons such as allylic and benzylic carbons. Quaternary carbon atoms are 'buried' and unlikely to be susceptible to cytochrome P450 enzymes. Alkenes and aromatic groups can be metabolized to diols.

Answer 2

Explanation:

Exposed groups such as terminal methyl groups are susceptible to oxidation by cytochrome P450 enzymes, as are activated carbons such as allylic and benzylic carbons. Quaternary carbon atoms are 'buried' and unlikely to be susceptible to cytochrome P450 enzymes. Alkenes and aromatic groups can be metabolized to diols