which of the following is most appropriate for thalassemia?
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Answer:Decrease of either beta or alpha globin chain of HbA
Explanation:
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Question: Which of the following is most appropriate for thalassemia?
(a) decrease of either beta (B) or alpha (a) globin chain of HbA
(b) decrease of alpha (a) cells of pancreas
(c) decrease of WBC count
(d) decrease of blood platelets
The most appropriate for thalassemia is decrease of either beta (B) or alpha (A) globin chain of HbA
Explanation:
- Thalassemia is caused due to decreased formation of alpha or beta chains of haemoglobin.
- The deletion occurs in globin gene that leads to decreased formation of globin chains.
- There are two types of thalassemia-the one is caused due to alteration in beta chain and other is caused due to alteration in alpha chain.
- This disease directly affects the red blood cell formation, that is, erythropoiesis.
- Alpha thalassemia is caused by reduced or absent synthesis of alpha globin chains, and beta thalassemia is caused by reduced or absent synthesis of beta globin chains.
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