Which of the following is not a correct statement for non-competitive irreversible inhibition of enzymes ?
1. V is decreased
2. K remains the same
3. ESI complex is formed
4. Inhibitor action can be overcome by increasing
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Answer:
v is decreased
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In case of non competitive irreversible inhibition of the enzyme the v remains constant
Option 1
Explanation:
- In case of non competitive irreversible inhibition of enzyme the substrate is prevented from binding with the enzyme. This occurs due to change in the arrangement of the enzyme.
- As a result of this the enzyme is actually be formed in a particular shape. Hence the k remains constant and the value of V in such a reaction is decreased. This occurs irreversibly and this continues forever
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