Question

Which of the following is the analogue of valine?

a. Isoleucine

b. Trifluoroleucine

c. Leucine

d. Cephamycin

Answer 1

Leucine and Isoleucine

Answer 2

The analog of valine is Option b) Trifluoroleucine.

• The analog of valine will inhibit valine's activity in mammalian cells.
• Suppose a particular bacteria can synthesize valine naturally.
• If it's analog i.e. Trifluoroleucine is introduced instead of valine.
• The nucleic acid synthesis will be inhibited. This gives us proper information regarding the kind of bonding, shape, and size of valine by comparing the results of valine and Trifluoroleucine.
• This is how Streptomyces lipmanni mutants were recognized by the use of Trifluoroleucine.