Question

Which of the following plasma protein can pass through the capillary endothelium.
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Answer 1

LIPID SOLUBLE OR SMALL MOLECULES CAN GO THROUGH CAPILLARY ENDOTHELIUM

Answer 2

Plasma protein

Explanation:

• The capillary endothelium is completely permeable to small molecules and electrolytes, but not to large protein molecules as it has a pore size of 6.5 nm.
• Plasma proteins for example albumin, are mostly restricted to the intravascular compartment and a colloid osmotic pressure (COP) of about 25 mmHg or 1.2 mosmol/kg is exerted.
• In the vascular system, the plasma COP antagonistic to fluid filtration across the capillary membrane, which is result of the hydrostatic pressure.
• Hence, albumin is a plasma protein which can move across capillary endothelium.