Question

Which of the following possibilities does not govern absorption according to the pH-partition hypothesis?.
a) pH at the absorption site
b)Lipid solubility of unionized drugs
c) Dissociation constant
d) the molecular size of the dru​

Answer 1

Answer:

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Answer 2

Answer:

Explanation: The pH-partition hypothesis tells that for drug compounds with molecular weight more than 100, that are transported by passive diffusion across the cell membrane, the process is governed by the capability of lipid solubility of unionized drugs, the dissociation constant of the drug and pH at the absorption site.