Question

which of the following procedure is not suitable for scale up​

Answer 1

Pls show us the question.

Answer 2

Which of the following procedures is not suitable for scale up?

a) Liquid-liquid extraction

b) Crystallisation

c) Distillation

d) Rotary evaporation

The correct answer to this question is option (d) Rotary evaporation.

Explanation:

• Rotary evaporation is the process in which the volume of the solvent is reduced by dispensing it as a thin layer all over the interior of a vessel that is at an elevated temperature and reduced pressure.  

• This encourages the speedy removal of excess solvent from less volatile samples.

• Rotary evaporation is carried out in a lab size equipment called a rotary vacuum evaporator, which is not meant for large scale processes.

• Instead of rotary evaporation, distillation would have to be carried out in scale up.