Which of the following statements is true for cell in G0 -stage of cell cycle : (A) Cells in G0 -stage are metabolically more active (B) Cells are metabolically inactive (C) Cells are metabolically active, but no longer proliferate in normal condition (D) None of the above
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Besides being the favorite carbon and energy source for the budding yeast Sacchromyces cerevisiae, glucose can act as a signaling molecule to regulate multiple aspects of yeast physiology. Yeast cells have evolved several mechanisms for monitoring the level of glucose in their habitat and respond quickly to frequent changes in the sugar availability in the environment: the cAMP/PKA pathways (with its two branches comprising Ras and the Gpr1/Gpa2 module), the Rgt2/Snf3-Rgt1 pathway
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(C) Cells are metabolically active, but no longer proliferate in normal condition
- The quiescent phase, also known as the G0 phase, is frequently used.
- Although the cell is no longer growing, it is nonetheless metabolically active.
- A cell at this stage is in a state of dormancy, meaning that it is not actively dividing or getting ready to divide, and it is not growing unless the organism needs it.
- Some cells briefly enter G0 before the start of G1 is signalled by an outside source. Other cells, such as mature heart muscle cells, that never or infrequently divide always stay in the G0 state.
- Not all cells follow the traditional pattern of the cell cycle, in which a freshly produced daughter cell instantly enters the interphase preparation stages, followed closely by the process of mitosis.
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