Which of these are necessary for initiation of blood
clotting process ?
JIPMER-2014)
(1) Prothrombinase and thrombin
(2) Tissue factor, Hageman factor and Ca?"
(3) Prothrombinase and K
(4) Prothrombinase, tissue factor and Ca?"
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Answer:
4 ) prothrombinase , tissue factor & ca
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All the components necessary for the
clotting process to proceed are found in the blood. As such, the proteins required for such clotting to take place are part of the intrinsic pathway of blood coagulation. This pathway involves a series of proteins, protein cofactors, and enzymes, which interact in reactions that take place on membrane surfaces. These reactions are initiated by tissue injury and result in the formation of a fibrin clot.
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