which ointment produce systemic effect
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In addition to local side effects, prolonged use of topical steroids can cause systemic side effects which are less common than those due to systemic corticosteroids. These occur especially in infants and elderly patients. The documented adverse effects are: Suppression of the hypothalamic-pituitary-adrenal axis.
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Explanation:
Clobetasol propionate is the most potent preparation associated with systemic side effects (600 -1000 times more potent compared to hydrocortisone) and has high skin absorption. Many factors increase the risk of developing side effects of topical corticosteroids
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