Question

which one of the following molecule allosterically stimulate a reaction found in glycolysis ? choose the option and explain :- a. acetyl - CoA b. calcium c. Glucose 1 - phosphate d. fructose 2, 6 - biphosphate. ( please explain the true option )​

Answer 1

Answer:

d

Explanation:

Fructose 2,6-bisphosphate was identified as a potent activator of phosphofructokinase. Fructose 2,6-bisphosphate activates phosphofructokinase (PFK) by increasing its affinity for fructose 6-phosphate and diminishing the inhibitory effect of ATP. In essence, Fructose 2,6-bisphosphate is an allosteric activator that shifts the conformational equilibrium of the enzyme from the T state to the R state.