Question

Which one of these is a systemic antacid
1. calcium carbonate
2. sodium bicarbonate
3. Potassium Sodium tartrate
4. None of the mentioned

Answer 1

Answer:

none of the mentioned is the answer

Answer 2

Sodium bicarbonate acts as a systemic antacid among the given substances.

• Antacid is a substance that is used for the neutralization of excessive gastric acid secretions.
• Antacids are generally weak bases.
• Antacids are classified based on their pharmacological properties as:

1. Systemic antacids
2. Non-systemic antacids.

• Systemic antacids form a soluble salt on reaction with the bicarbonate ion, so they get absorbed into the systemic circulation. An example of such a compound includes Sodium bicarbonate.
• The anion part, that is bicarbonate neutralizes the hydrogen ions of the acid, whereas the cation, that is sodium, forms a salt with the anion part of the acid, which is soluble.
• Non-systemic antacids form an insoluble salt on reaction with bicarbonate ion, so they don't get absorbed systemically. Examples include Aluminum hydroxide and Magnesium hydroxide.