Question

Which phase shown a notch in the cytoplasm in between central region

Answer 1

Notch proteins are transparent membrane receivers for an intercellular signaling path that affects many cell fate decisions throughout the Metazoa.  

Extracellular domains of Notch receivers are composed largely of tandemly repeated epidermal growth factor domains.  

Main class of Notch ligands which is commonly known as DSL ligands are transparent membrane proteins with multiple EGF domains.  

Main signaling route linked with Notch with its ligands pushes proteolytic processing of Notch.  

It emits cytoplasmic domain of Notch from membrane upon which it travels to nucleus and forms part of transcriptional activation complex.

Answer 2

cytokinesis is the right answer.