Question

Which point mutation would be most likely to have a catastrophic effect on the functioning of a protein?
A) a base substitution
B) a base deletion near the start of a gene
C) a base deletion near the end of the coding sequence, but not in the terminator codon
D) deletion of three bases near the start of the coding sequence, but not in the initiator codon
E) a base insertion near the end of the coding sequence, but not in the terminator codon

Answer 1

Answer:

a base substitution

Explanation:

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Answer 2

A base substitution is a type of point mutation which would be most likely to have a catastrophic effect on the function of a protein

option A

Explanation:

• mutation is defined as the change in the pattern of the nucleotides which is present in a DNA. Mutation can be of several types point mutation means the mutation which takes place at a single place of the DNA. the most difference which a mutation suffers is when a base substitution occurs.

• This means that one of the nitrogenous base is replaced by another nitrogenous base.

To know more about mutation,

What is gene mutation what is its role in organic evolution? - Brainly.in

https://brainly.in/question/6596285