Question

Which property of DNA double helix led Watson and Crick to hypothesise semi-conservative mode of DNA replication? Explain.

Answer 1

Watson and Crick observed that the two strands of DNA are anti-parallel and complementary to each other with respect to their base sequences. This type of arrangement in DNA molecule led to the hypothesis that DNA replication is semi-conservative.

Answer 2

Answer:

• Watson and Crick observed that the two strands of DNA are anti-parallel and complementary to each other with respect to their base sequences.
• This type of arrangement in DNA molecule led to the hypothesis that DNA replication is semi-conservative.
• It means that the double stranded DNA molecule separates and then, each of the separated strand acts as a template for the synthesis of a new complementary strand.
• As a result, each DNA molecule would have one parental strand and a newly synthesized daughter strand.
• Since only one parental strand is conserved in each daughter molecule, it is known as semi-conservative mode of replication.