which steps of krebs cycle operates substrate level phosphorylation
Answers
Answer:
Substrate-level phosphorylation occurs in the cytoplasm of cells during glycolysis and in mitochondria either during the Krebs cycle or by MTHFD1L (EC 6.3.4.3), an enzyme interconverting ADP + phosphate + 10-formyltetrahydrofolate to ATP + formate + tetrahydrofolate (reversibly), under both aerobic and anaerobic
During the Krebs cycle, the succinyl CoA is converted into Succinate in the presence of a succinic CoA synthetase enzyme. This reaction release ATP or GTP molecules by substrate-level phosphorylation. This is the fifth step in the krebs cycle.
• Krebs cycle is also known as the Citric acid cycle. Substrate level phosphorylation provides a quicker and less efficient source of ATP molecules.
• Substrate level phosphorylation occurs in the cytoplasm during glycolysis or mitochondrial matrix during the Krebs cycle.