Question

Which type of cells located in gastric glands is responsible for the release of histamine

Answer 1

Gastric glands are located in different areas of the stomach. Namely the fundic glands, the cardiac glands, and the pyloric glands. The glands and gastric pit are located in the lining of the stomach. The glands are themselves in the lamina propria of the mucous membrane and they open on the basis of the gastric pit formed by the epithelium.  Different cells of the glands spray mucous, pepsinogen, hydrochloric acid, internal factor, gastrin, histamine and bicarbonate.

Perital cells ("perital" means "related to the wall") are found on the walls of tubes. Perital cells sprinkle the main component of hydrochloric acid-gastric acid. It should be easily available for supply of stomach in the stomach, and therefore, by their position in the walls, their secret network of good channels called Canaliculi can project in all areas of Gastric-Pit Lumen. Another important secretion of family cells is the internal factor. The internal factor is a glycoprotein which is essential for the absorption of vitamin B12.

Perital cells produce and release bicarbonate ions in response to histamine release from surrounding ECL, and therefore pH plays an important role in the buffering system.  

Stores cells like enterocromffine and pH of the stomach becomes very high when histamine releases. Histamine release is stimulated with gastrin secretion from G cells. Histamine stimulates production and release of bicarbonate ions from perital cells to blood and proton to abdomen lumen. When stomach pH decreases (becomes more acidic), ECL stop releasing histamine.

G cells are most commonly found in the pyloric glands in the pylorous antrum; Some are found in duodenam and other tissues. G cells spray gastrines The gastric pit of these glands is much deeper than others and here lies the secret of gastrin's blood flow, not lumen

Answer 2

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Enterochromaffin-like cells or ECL cells are a type of neuroendocrine cell found in the gastric glands of the gastric mucosa beneath the epithelium, in particular in the vicinity of parietal cells, that aid in the production of gastric acid via the release of histamine.