which vaccine is used for polio and tuberculosis
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Tuberculosis (TB) vaccines are vaccinations intended for the prevention of tuberculosis. Immunotherapy as a defence against TB was first proposed in 1890 by Robert Koch.[1] Today, the only effective tuberculosis vaccine in common use is the Bacillus Calmette-Guérin (BCG) vaccine, first used on humans in 1921.[2] About three out of every 10,000 people who get the vaccine experience side effects, which are usually minor except in severely immuno-depressed individuals. While BCG immunization provides fairly effective protection for infants and young children,[3] (including defence against TB meningitis and miliary TB),[4][5] its efficacy in adults is variable,[6] ranging from 0% to 80%.[4][7] Several variables have been considered as responsible for the varying outcomes.[4] Demand for TB immunotherapy advancement exists because the disease has become increasingly drug-resistant.[1]
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