Which vitamen is required as a prosthetic group for pyruvate dehydrogenase?
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Pyruvate dehydrogenase is a multi-enzyme complex that uses three enzymes: E1: Pyruvate dehydrogenase which uses thiamine pyrophosphate(TPP) as its prosthetic group. E2: Dihydrolipoyl transacetylase which uses lipoamide and coenzyme A (also known as coASH) as its prosthetic groups.
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