Biology, asked by bioexpress, 1 month ago

wht is the origin of replication ​

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Answered by ՏɑɾíƙɑՏօƖɑղƙí
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wht is the origin of replication _??

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Origin of replication (ori): This is a sequence from where replication starts and any piece of DNA when linked to this sequence can be made to replicate within the host cells. If a piece of DNA, is somehow transferred into an alien organism, most likely, this piece of DNA would not be able to multiply itself in the progeny cells of the organism. But when it gets integrated into the genome of the recipient, it may multiply and be inherited along with the host DNA. This is because the alien piece of DNA has become a part of a chromosome, which has the ability to replicate. In a chromosome, there is a specific DNA sequence called the origin of replication. Thus, an allen DNA is linked with the origin of replication, so that, this alien piece of DNA can replicate and multiply itself in the host organism. This can also be called cloning or making multiple identical copies of any template DNA. This sequence is also responsible for controlling the copy number of the linked DNA. So, if one wants to recover many copies of the target DNA it should be cloned in a vector whose origin support high copy number.

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