Chemistry, asked by Unsaqeen999, 5 hours ago

Why a claisen condensation is not obtained from an ester that has only one alpha hydrogen ?

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Answered by withluckygamingstyle
2

Answer:

The newly formed β-keto ester or β-diketone is then isolated. ... That is, Claisen condensation does not work with substrates having only one α-hydrogen because of the driving force effect of deprotonation of the β-keto ester in the last step.

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