why antibiotics does not work on E. coli
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Answer:
Today, many disease-causing bacteria acquire resistance genes, which make antibiotic treatment ineffective. Especially, one gene, CTX-M-15, encoding an extended spectrum beta-lactamase (ESBL) can lead to resistance in E. coli causing urinary tract infections.
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antibiotics do not work on them because resistant bacteria such as E.Coli change their cell walls slightly, so the antibiotics cannot attach or they produce enzymes to disable the antibiotics.
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