Why are lysosomes known as suicide bags
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Explanation:
It was supposed that if the organelle membrane could be disrupted inside the cell, hydrolases would have access to cytosol with as a result a dramatic degradation of vital components leading to cell death. That led to the concept of lysosomes as “suicide bags
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- ɪᴛ ᴡᴀs sᴜᴘᴘᴏsᴇᴅ ᴛʜᴀᴛ ɪғ ᴛʜᴇ ᴏʀɢᴀɴᴇʟʟᴇ ᴍᴇᴍʙʀᴀɴᴇ ᴄᴏᴜʟᴅ ʙᴇ ᴅɪsʀᴜᴘᴛᴇᴅ ɪɴsɪᴅᴇ ᴛʜᴇ ᴄᴇʟʟ, ʜʏᴅʀᴏʟᴀsᴇs ᴡᴏᴜʟᴅ ʜᴀᴠᴇ ᴀᴄᴄᴇss ᴛᴏ ᴄʏᴛᴏsᴏʟ ᴡɪᴛʜ ᴀs ᴀ ʀᴇsᴜʟᴛ ᴀ ᴅʀᴀᴍᴀᴛɪᴄ ᴅᴇɢʀᴀᴅᴀᴛɪᴏɴ ᴏғ ᴠɪᴛᴀʟ ᴄᴏᴍᴘᴏɴᴇɴᴛs ʟᴇᴀᴅɪɴɢ ᴛᴏ ᴄᴇʟʟ ᴅᴇᴀᴛʜ. ᴛʜᴀᴛ ʟᴇᴅ ᴛᴏ ᴛʜᴇ ᴄᴏɴᴄᴇᴘᴛ ᴏғ ʟʏsᴏsᴏᴍᴇs ᴀs “sᴜɪᴄɪᴅᴇ ʙᴀɢs”.
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