Question

Why atoh1 is called basic helix loop helix transcription factor?

Answer 1

A basic helix-loop-helix (bHLH) is a protein structural motif that characterizes one of the largest families of dimerizing transcription factors. bHLH transcription factors are often important in development or cell activity. BMAL1-Clock is a core transcription complex in the molecular circadian clock.

Answer 2

Answer:

ATOH1 is a mammalian homolog of the Drosophila melanogaster gene atonal. ATOH1 is considered part of the Notch signaling pathway. In 2009, ATOH1 was identified as a tumor suppressor gene.