why beta cells would have a greater concentration of rough endoplasmic reticulum and ribosomes than some other cell types.
Answers
Endoplasmic reticulum (ER) and Golgi apparatus are subjected to mass spectrometry have uncovered over a thousand different proteins assigned to the ER and Golgi apparatus of rat liver.
In turn, led to the uncovering of several hundred proteins of poorly understood function and, through hierarchical clustering, showed that proteins distributed in patterns suggestive of microdomains in cognate organelles.
The beta cells are found in the pancreas to store and release insulin. They have a higher concentration of rough endoplasmic reticulum and ribosomes than some other cell types.
The endoplasmic reticulum link to beta cell survival and insulin production. Beta-cell failure in mice model of type 2 diabetes is due to increased ribosomal biogenesis.