Why blood does not clot in blood vessels
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It's caused by a deficiency of von Willebrand factor, which helps blood platelets clump together and stick to the blood vessel wall. This is a necessary step for normal blood clotting.
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Here is your answer ....
Liver produces an anticoagulant, hetero-polysaccharide called heparin which prevent clotting inside the blood vessels. Heparin is a highly sulfated glycosaminoglycan and is also used to form an inner anticoagulant surface on experimental and medical devices.
Fibrinogen is a glycoprotein that helps in the formation of blood clots.
Thrombin is a blood coagulation factor.
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