Question

Why do individuals deficient of glucose-6-phosphate dehydrogenase have increased resistance to malaria infection?

Answer 1

Answer:

As G6PD deficiency leads to increased oxidative stress in red blood cells, this may in turn have a negative influence on the parasite. As such, individuals who possess this mutation have some protection against malaria.

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Answer 2

Answer:

the person who have glucose 6 phosphate dehydrogenase has disease called sickle cell anaemia.their RBCs are sickle shaped and unable to carry oxygen in them.

malarial parasites live in RBC of human .

due to sickle shaped RBC ,malarial parasite cannot live in it.

so those people evn though attacked by malarial parasite ,do not develop the symptoms of malaria