Why do mutations in genes that encode dna repair enzymes and chromosome segregation often produce a predisposition to cancer?
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Why and chromosome segregation ? that affect high rates of that may convert proto-oncogenes into oncogenes or inactivate tumor-suppressor .
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Why do mutations in genes that encode DNA repair enzymes and chromosome segregation often produce a predisposition to cancer? ... Normally, somatic cells do not express telomerase; their telomeres progressively shorten with each cell division until vital genes are lost and the cells undergo apoptosis.
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