Question

why do normal Red blood cells become elongated sickle shape structure in a person suffering from sickle cell anaemia​

Answer 1

because their is abnormalities in the cells. the structure of the cell becomes every hard as compare to first.

Answer 2

Answer:

Low oxygen tension

Explanation:

This defect is caused by the substitution of Glutamic acid (Glu) by Valine (Val) at the sixth position of the beta globin chain of the haemoglobin molecule. This mutant haemoglobin undergo polymerisation under low oxygen tension causing the change inn the shape of the RBC from biconcave disc to elongated sickle like structure.