Why do people acquire viral infection even in the presence of innate immune barriers
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A virus-bound antibody binds to receptors, called Fc receptors, on the surface of phagocytic cells and triggers a mechanism known as phagocytosis, by which the cell engulfs and destroys the virus. Finally, antibodies can also activate the complement system, which opsonises and promotes phagocytosis of viruses.
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Viruses initially activate the innate immune system, which recognizes viral components through pattern-recognition receptors (PRRs) (1-3). On the other hand, acquired immunity plays a major role in the responses to re-infection with viruses.
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