Why do we find more lysosomes in an old cell in comparison to a newly formed cell ?
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Answer:
Lysosomes are an important cell organelle found within eukaryotic animal cells. Due to their peculiar function, they are also known as the “suicide bags” of the cell.
The term was coined by Christian de Duve, a Belgian biologist, who discovered it and ultimately got a Nobel Prize in Medicine or Physiology in the year 1974.
Let us have a detailed overview of lysosome structure, functions and diseases associated with it.
Lysosome Definition
“Lysosomes are sphere-shaped sacs filled with hydrolytic enzymes that have the capability to break down many types of biomolecules.”
In other words, lysosomes are membranous organelles whose specific function is to breakdown cellular wastes and debris by engulfing it with hydrolytic enzymes.
Lysosome Structure
Lysosomes are membrane-bound organelles and the area within the membrane is called the lumen, which contains the hydrolytic enzymes and other cellular debris.
The diagram below shows the lysosome structure within a cell.
Lysosomes
Lysosome diagram showcasing enzyme complexes within the single-walled membrane
The pH level of the lumen lies between 4.5 and 5.0, which makes it quite acidic. It is almost comparable to the function of acids found in the stomach.
Besides breaking down biological polymers, lysosomes are also involved in various other cell processes such as counting discharged materials, energy metabolism, cell signalling, and restoration of the plasma membrane.
The sizes of lysosomes vary, with the largest ones measuring in more at than 1.2 μm. But they typically range from 0.1 μm to 0.6 μm.
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People with these disorders are missing important enzymes (proteins that speed up reactions in the body). Without those enzymes, the lysosome isn't able to break down these substances. When that happens, they build up in cells and become toxic. They can damage cells and organs in the body.