Chemistry, asked by Belwalker, 4 months ago

Why do we use furosemide as a control group in diuretic activity research?

Answers

Answered by Anonymous
3

Explanation:

Diuretics are banned in all sports because they can cause rapid weight loss and can act as masking agents (to hide the effects of other prohibited substances) both in and out of competition. ... For diuretics, the primary permitted therapeutic use is for hypertension (WADA, 2008b).

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Answered by Goldenjungkookie
6

Answer:

Wistar albino rats were randomly divided into five groups of six rats each. Control group, furosemide treated group, and P. harmala treated group. Control group was treated with 2 ml/100 g of body weight methanol vehicle, furosemide treated group was treated with furosemide 10 mg/kg orally (Da Silva et al., 2015, Hailu and Engidawork, 2014). Herbal treated group was subdivided into three subgroups, they were treated with 150, 300 and 450 mg/kg doses of methanolic extracts of P. harmala (MEPH), respectively. All administered drugs were given orally.

Each animal was placed in isolation in metabolic cages, 24 h prior to commencement of the experiment for adaptation and then fasted overnight with free access to water. Urine samples were collected after 5 h and 24 h of the last dose. The urine samples were filtered and finally stored at −20 °C for electrolyte analyses.

Explanation:

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