Biology, asked by saikireeti6825, 1 year ago

Why does histamine given subcutaneously cause less fall in blood pressure than when given intravenously?

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Answered by Ayesha059

0

When injected intravenously, histamine causes most blood vessels to dilate, and hence causes a fall in the blood pressure.This is a key mechanism in anaphylaxis, and is thought to be caused when histamine releases nitric oxide, endothelium-derived hyperpolarizing factors and other compounds from the endothelial cells.

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