Question

Why does our immune system fail against pathogens like trypanosoma and plasmodium​

Answer 1

Tʀʏᴘᴀɴᴏsᴏᴍᴀ ʙʀᴜᴄᴇɪ ᴘᴀʀᴀsɪᴛᴇs sᴜᴄᴄᴇssғᴜʟʟʏ ᴇᴠᴀᴅᴇ ᴛʜᴇ ʜᴏsᴛ ɪᴍᴍᴜɴᴇ sʏsᴛᴇᴍ ʙʏ ᴘᴇʀɪᴏᴅɪᴄᴀʟʟʏ sᴡɪᴛᴄʜɪɴɢ ᴛʜᴇ ᴅᴇɴsᴇ ᴄᴏᴀᴛ ᴏғ ᴠᴀʀɪᴀɴᴛ sᴜʀғᴀᴄᴇ ɢʟʏᴄᴏᴘʀᴏᴛᴇɪɴ (VSG) ᴀᴛ ᴛʜᴇ ᴄᴇʟʟ sᴜʀғᴀᴄᴇ. Eᴀᴄʜ ᴘᴀʀᴀsɪᴛᴇ ᴇxᴘʀᴇssᴇs VSGs ɪɴ ᴀ ᴍᴏɴᴏᴀʟʟᴇʟɪᴄ ғᴀsʜɪᴏɴ ᴛʜᴀᴛ ɪs ᴛɪɢʜᴛʟʏ ʀᴇɢᴜʟᴀᴛᴇᴅ.

Answer 2

Answer:

Malaria causes approximately 212 million cases and 429 thousand deaths annually. Plasmodium falciparum is responsible for the vast majority of deaths (99%) than others.