Why does patient of ada requires periodic infusion of genetically enginered lymphocytes and suggest a possible remedy?
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Lymphocytes not immortal / short lived, hence patient requires periodic infusion of such genetically engineered lymphocytes, however if a gene producing ADA is isolated from marrow cells, and introduced into the cells at early embryonic stages it could be a permanent cure.
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➖The introduction of genetically engineered lymphocyte into an ADA (Adenosine Deaminase) deficiency patient is not a permanent cure as applying this technique for once is not sufficient.
➖The deficiency needs several periodic infusions of such lymphocytes as these cells cannot survive long.
➖If the gene producing Adenosine Deaminase is isolated from bone marrow and is introduced into the cells of an organism in early embryonic cells, it can be a permanent cure of ADA deficiency.
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