Question

Why don't amines undergo nucleophilic substitution?

Answer 1

Answer:

Epoxides are an exception, since they relieve their ring strain when they undergo nucleophilic substitution, with activation by acid being optional: ... Under substitution conditions, amines proceed all the way to form quaternary salts, which makes it difficult to control the extent of the reaction.

I hope this will help ❤

Answer 2

Explanation:

Epoxides are an exception, since they relieve their ring strain when they undergo nucleophilic substitution, with activation by acid being optional: ... Under substitution conditions, amines proceed all the way to form quaternary salts, which makes it difficult to control the extent of the reaction.