Biology, asked by johnfrancis1278, 10 months ago

Why drug concentrations are more often measured in the plasma rather than the whole blood serum

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Answered by athulliagiri
1

Answer:Blood is composed of plasma and red blood cells (RBCs). Serum is the fluid obtained from blood after it is allowed to clot. Serum and plasma do not contain identical proteins. RBCs may be considered a cellular component of the body in which the drug concentration in the serum or plasma is in equilibrium, in the same way as with the other tissues in the body. Whole blood samples are generally harder to process and assay than serum or plasma samples. Plasma may be considered a liquid tissue compartment in which the drug in the plasma fluid equilibrates with drug in the tissues and cellular components.

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