Biology, asked by omparkash658, 5 months ago

Why drug during absorption, distribution and excretion show non-linear curve

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Answered by Anonymous

1

Answer:

Besides saturation of plasma protein-binding or carrier-mediated systems, drugs may demonstrate nonlinear pharmacokinetics due to a pathologic alteration in drug absorption, distribution, and elimination. For example, aminoglycosides may cause renal nephrotoxicity, thereby altering renal drug excretion.

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