Question

Why epistaxis occur in excessive use of analgesics?

Answer 1

Hy,
Analgesics doesn't cause epistaxis, it does causes peptic ulcers. Actually, the mechanism of action of Analgesics itself includes that analgesics block the COX-1 and COX-2 inhibitors. Due to their blockage, PGE2 inhibitors act and stop secretion of PGE due to which peptic ulcers are formed in stomach.
Hope it helps
Regards
Dr Chinmay
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